abstract：BACKGROUND AND OBJECTIVE:A novel, noninvasive technology, utilizing suction-coupled radiofrequency (RF) heating and ultra-short pulse duration, high-voltage electrical pulses was studied for its efficacy and safety on adipose tissue reduction. METHODS:Twenty-one subjects underwent treatment of their abdominal fat once...

journal_title：Lasers in surgery and medicine

authors： Boisnic S,Divaris M,Nelson AA,Gharavi NM,Lask GP

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Repair of peripheral nerve injuries remains a major challenge in restorative medicine. Effective therapies that can be used in conjunction with surgical nerve repair to improve nerve regeneration and functional recovery are being actively investigated. It has been demonstrated by a number of pe...

journal_title：Lasers in surgery and medicine

authors： Anders JJ,Moges H,Wu X,Erbele ID,Alberico SL,Saidu EK,Smith JT,Pryor BA

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Pores in the sclera are a candidate pathway for aqueous transport and therefore can be utilized to decrease the intraocular pressure (IOP) in glaucomatous eyes. Since pore formation is a well-known mechanism for stress relaxation in solids, laser-induced creation of pores in cartilage increase...

journal_title：Lasers in surgery and medicine

authors： Baum OI,Sobol EN,Bolshunov AV,Fedorov AA,Khomchik OV,Omelchenko AI,Shcherbakov EM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Port-wine stain (PWS) is a congenital, progressive vascular malformation of the dermis. The use of optical coherence tomography (OCT) for the characterization of blood vessels in PWS skin has been demonstrated by several groups. In the past few years, advances in OCT technology have greatly in...

journal_title：Lasers in surgery and medicine

authors： Liu G,Jia W,Nelson JS,Chen Z

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The identification of parathyroid glands can be a major problem in parathyroid surgery. The purpose of this study was to evaluate the feasibility of optical coherence tomography (OCT) in distinguishing between parathyroid tissue, thyroid tissue, lymph nodes, and adipose tissue. METHODS:Ex vivo...

journal_title：Lasers in surgery and medicine

authors： Ladurner R,Hallfeldt KK,Al Arabi N,Stepp H,Mueller S,Gallwas JK

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Infrared neural stimulation (INS) has recently evoked interest as an alternative to electrical stimulation. The mechanism of activation is the heating of water, which induces changes in cell membrane potential but may also trigger heat sensitive receptors. To further elucidate the mechanism, wh...

journal_title：Lasers in surgery and medicine

authors： Liljemalm R,Nyberg T,von Holst H

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interstitial photodynamic therapy (iPDT) of non-resectable recurrent glioblastoma using 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) has shown a promising outcome. It remained unclear, however, to what extent inter- and intra-tumoural differences of PpIX concentrations influence...

journal_title：Lasers in surgery and medicine

authors： Johansson A,Faber F,Kniebühler G,Stepp H,Sroka R,Egensperger R,Beyer W,Kreth FW

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Photodynamic therapy (PDT) offers the potential for enhanced treatment of nonmelanoma skin cancer (NMSC) with minimal scarring. Yet, PDT has not achieved consistent long term effectiveness to gain widespread clinical acceptance for treatment of skin cancer. Therapeutic response varies between practitioners, ...

journal_title：Lasers in surgery and medicine

authors： Saager RB,Cuccia DJ,Saggese S,Kelly KM,Durkin AJ

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Photodynamic therapy (PDT) is a minimally invasive therapeutic modality for the treatment of neoplastic and non-neoplastic diseases. The photochemical interaction of light, photosensitizer (PS) and molecular oxygen produces singlet oxygen which induces cell death. The effectiveness of zinc sulf...

journal_title：Lasers in surgery and medicine

authors： Manoto SL,Houreld NN,Abrahamse H

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Photodynamic therapy (PDT) has become one of the emerging options in management of cancer and other diseases. The major goal of PDT is to kill cancer cell without causing any adverse effect to the normal cells. PDT in combination of different therapeutic agents is being evaluated to improve the...

journal_title：Lasers in surgery and medicine

authors： Ahn JC,Biswas R,Chung PS

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cutaneous and mucocutaneous leishmaniasis are diseases characterized by skin or mucosal manifestations. In the new world, Leishmania braziliensis is the main etiological agent of cutaneous leishmaniasis, condition that may evolve to the mucocutaneous form. The therapeutic arsenal routinely empl...

journal_title：Lasers in surgery and medicine

authors： Barbosa AF,Sangiorgi BB,Galdino SL,Barral-Netto M,Pitta IR,Pinheiro AL

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Biofilm-related diseases such as caries and periodontal disease are prevalent chronic oral infections which pose significant oral and general health risks. Biofilms are sessile communities attached to surfaces. Photodynamic therapy (PDT) has been demonstrated to have a significant anti-microbi...

journal_title：Lasers in surgery and medicine

authors： Mang TS,Tayal DP,Baier R

更新日期：2012-09-01 00:00:00

abstract：INTRODUCTION:Patient demand for non-surgical, non-invasive, and no-downtime wrinkle reduction treatment procedures has grown dramatically over the past decade as new treatments and technologies have been introduced. This study was performed in order to evaluate the safety and efficacy of the TriPollar radiofrequency (R...

journal_title：Lasers in surgery and medicine

authors： Shapiro SD,Eros Y,Abrahami Y,Leviav A

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The treatment of acne scars with fractional CO(2) lasers is gaining increasing impact, but has so far not been compared side-by-side to untreated control skin. OBJECTIVE:In a randomized controlled study to examine efficacy and adverse effects of fractional CO(2) laser resurfacing for atrophic acne scars com...

journal_title：Lasers in surgery and medicine

authors： Hedelund L,Haak CS,Togsverd-Bo K,Bogh MK,Bjerring P,Haedersdal M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Photodynamic therapy (PDT) may be a less invasive treatment for lung cancer. Our newly developed surface layer-preserving PDT (SPPDT) technique enables us to irradiate deep tumor while preserving the overlying tissue. The aim of this basic study was to verify that the SPPDT technique might be ...

journal_title：Lasers in surgery and medicine

authors： Kawakubo M,Eguchi K,Arai T,Kobayashi K,Hamblin MR

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Low-intensity laser irradiation (LILI) has been used to modulate a variety of biological processes, including diabetic wound healing. The mechanism of action is thought to exist primarily with the mitochondria. This study aimed to determine the effect of irradiation on normal, diabetic, and isc...

journal_title：Lasers in surgery and medicine

authors： Houreld NN,Masha RT,Abrahamse H

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Low-level laser therapy (LLLT) is a noninvasive treatment for a wide-assortment of medical ailments. A recent application is for noninvasive body slimming. A Level 1 clinical study was completed and recorded a significant reduction in circumferential measurements across waist, hips, and thighs compared to pl...

journal_title：Lasers in surgery and medicine

authors： Jackson RF,Stern FA,Neira R,Ortiz-Neira CL,Maloney J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Pulsed dye laser (PDL) is the first choice for treatment of port wine stains (PWS). However, outcome is highly variable and only a few patients achieve complete clearance. The objective of the study was to compare efficacy and safety of single pass PDL with double pass PDL at a 6 minute interval. METHODS:We...

journal_title：Lasers in surgery and medicine

authors： Peters MA,van Drooge AM,Wolkerstorfer A,van Gemert MJ,van der Veen JP,Bos JD,Beek JF

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Current laser therapy of port wine stain (PWS) birthmarks with a single laser pulse (SLP) does not produce complete lesion removal in the majority of patients. To improve PWS therapeutic efficacy, we evaluated the performance of an approach based on multiple laser pulses (MLP) to enhance blood ves...

journal_title：Lasers in surgery and medicine

authors： Jia W,Tran N,Sun V,Marinček M,Majaron B,Choi B,Nelson JS

更新日期：2012-02-01 00:00:00

abstract：INTRODUCTION:The pulsed dye laser (PDL) using varying fluences and pulse durations have been used to treat hemangiomas. This study aims to examine the efficacy and safety of the 595-nm PDL for the treatment of infantile hemangiomas using short (1.5-3 milliseconds) versus long (10 milliseconds) pulse durations and high ...

journal_title：Lasers in surgery and medicine

authors： Tay YK,Tan SK

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Hyperhidrosis is a condition that affects a large percentage of the population and has a significant impact on peoples' lives. This report presents a technical overview of a new noninvasive, microwave-based device for creating thermolysis of sweat glands. The fundamental principles of operatio...

journal_title：Lasers in surgery and medicine

authors： Johnson JE,O'Shaughnessy KF,Kim S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Kenalog application onto surgical wounds has been used to control dynamic pain following Laser-Assisted-Uvulo-Palatoplasty (LAUP) with good results in our department. When the effect was sub-optimal, insufficient ointment over the superior-lateral corner of wounds were always noted. Fulfilling...

journal_title：Lasers in surgery and medicine

authors： Li LP,Lee SS,Chuang AY,Niddam DM,Tung TH,Chen JK

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:Dental composite restorative materials are color matched to the tooth and are difficult to remove by mechanical means without excessive removal or damage to peripheral enamel and dentin. Lasers are ideally suited for selective ablation to minimize healthy tissue loss when replacing existing restorations, seal...

journal_title：Lasers in surgery and medicine

authors： Chan KH,Hirasuna K,Fried D

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Photodynamic therapy (PDT) using topical aminolevulinic acid (ALA) depends on local drug uptake, metabolism to porphyrins, and depth of light penetration using different wavelengths. Topical ALA-PDT has limited depth of drug penetration. We studied induced porphyrin distribution and PDT after intradermal ALA...

journal_title：Lasers in surgery and medicine

authors： Sakamoto FH,Doukas AG,Farinelli WA,Tannous Z,Su Y,Smith NA,Zurakowski D,Anderson RR

更新日期：2011-09-01 00:00:00

abstract：:Photochemical internalization (PCI) is a method for intracellular delivery of hydrophilic macromolecular drugs with intracellular targets as well as other drugs with limited ability to penetrate cellular membranes. Such drugs enter cells by means of endocytosis and are to a large extent degraded by hydrolytic enzymes ...

journal_title：Lasers in surgery and medicine

authors： Weyergang A,Selbo PK,Berstad ME,Bostad M,Berg K

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Thermal lasers are routinely used to treat certain retinal disorders although they cause collateral damage to photoreceptors. The current study evaluated a confined, non-conductive thermal, 3-nanosecond pulse laser in order to determine how to produce the greatest therapeutic range without cau...

journal_title：Lasers in surgery and medicine

authors： Wood JP,Plunkett M,Previn V,Chidlow G,Casson RJ

更新日期：2011-08-01 00:00:00

abstract：INTRODUCTION:Photodynamic therapy is a proven therapeutic modality in the management of variety of pathologies involving the human body. Our aim in this clinical study is to prospectively evaluate the outcome following interstitial photodynamic therapy for patients with vascular anomalies. Patients' reports on quality ...

journal_title：Lasers in surgery and medicine

authors： Jerjes W,Upile T,Hamdoon Z,Mosse CA,Akram S,Morley S,Hopper C

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:It is recognized that hypoxic/ischemic conditions leading to production of reactive oxygen species (ROS) are an important mediator of angiogenesis in the wound-healing process. Recently, low level light irradiation at 635 nm, which is used in many clinical fields, was found to decrease intrace...

journal_title：Lasers in surgery and medicine

authors： Lim WB,Kim JS,Ko YJ,Kwon H,Kim SW,Min HK,Kim O,Choi HR,Kim OJ

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:Clinical laser settings have traditionally been calibrated on abdominal skin to predict and anticipate patterns of injuries in facial skin. This experimental approach has limitations as facial skin and abdominal skin have differences that may influence the depth of laser injury. OBJECTIVE:The primary obje...

journal_title：Lasers in surgery and medicine

authors： Bailey SH,Brown SA,Kim Y,Oni G,Abtahi F,Richardson JA,Hoopman J,Barton F,Kenkel JM

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interstitial laser thermotherapy was used to treat rat liver tumours. The aim was to investigate the influence of temperature and temporary hepatic inflow occlusion on tumour growth and blood perfusion. STUDY DESIGN/MATERIALS AND METHODS:Liver tumours were treated at 44°C at the tumour border ...

journal_title：Lasers in surgery and medicine

authors： Sturesson C,Ivarsson K,Stenram U,Andersson-Engels S,Tranberg KG

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Previously, we have shown that a 43°C pretreatment can provide thermotolerance to a following, more severe, thermal stress at 45°C. Using cells that lack the Hsp70 gene, we have also shown that there is still some thermotolerance in the absence of HSP70 protein. The purpose of this study was t...

journal_title：Lasers in surgery and medicine

authors： Beckham JT,Wilmink GJ,Opalenik SR,Mackanos MA,Abraham AA,Takahashi K,Contag CH,Takahashi T,Jansen ED

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:Leg telangiectasias have been reported to have been treated with a variety of lasers. This study was designed to measure response to treatment of leg telangiectasias with a unique coupled 585 nm and 1064 nm pulse. METHODS:Sixty female patients (24-62 y.o., skin types II-IV) with leg vein varicosities were...

journal_title：Lasers in surgery and medicine

authors： Trelles MA,Weiss R,Moreno-Moragas J,Romero C,Vélez M,Alvarez X

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to examine the influence of implant bed preparation, using either Er:YAG laser ablation, piezoelectric surgery or drill osteotomy, on osseointegration of titanium dental implants after 4, 6, and 8 weeks. MATERIAL AND METHODS:A total of 108 implants (Camlog) were plac...

journal_title：Lasers in surgery and medicine

authors： Stübinger S,Biermeier K,Bächi B,Ferguson SJ,Sader R,von Rechenberg B

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The main factors in photodynamic therapy (PDT) are: photosensitizer retention, photon absorption, and oxygen supply. Each factor has its unique set of problems that poses limitation to the treatment. Both light delivery and oxygen supply are significant bottlenecks in PDT. Vascular closure duri...

journal_title：Lasers in surgery and medicine

authors： Yang L,Wei Y,Xing D,Chen Q

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:LED photomodulation has been shown to profoundly influence cellular behavior. A variety of parameters with LED photomodulation can alter cellular response in vitro. The effects of one visible and one infrared wavelength were evaluated to determine the optimal ratio to produce a net increase in ...

journal_title：Lasers in surgery and medicine

authors： McDaniel DH,Weiss RA,Geronemus RG,Mazur C,Wilson S,Weiss MA

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:High-power laser has recently become a physical stimulus for bone regeneration. Little is known about how high-power laser irradiation affects osteoblast differentiation. This study investigated osteoblast responses to high-power laser and combined irradiation with BMP-2 treatment. STUDY DESIG...

journal_title：Lasers in surgery and medicine

authors： Kim IS,Cho TH,Kim K,Weber FE,Hwang SJ

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Autofluorescence (AF) emission is an intrinsic parameter that can provide real-time information on morpho-functional properties of biological tissue, being strictly related with their biochemical composition and structural organization. The diagnostic potentials of AF-based techniques have been...

journal_title：Lasers in surgery and medicine

authors： Croce AC,De Simone U,Freitas I,Boncompagni E,Neri D,Cillo U,Bottiroli G

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Primary blast injury is produced by shock waves. Blast injuries to lungs are extremely critical threats to survival, but their etiology is largely undefined. The majority of animal models for these injuries use explosive or complex experimental settings, limiting the laboratory study of blast ...

journal_title：Lasers in surgery and medicine

authors： Satoh Y,Sato S,Saitoh D,Tokuno S,Hatano B,Shimokawaji T,Kobayashi H,Takishima K

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In laser retinal photocoagulation, hundreds of dot-like burns are applied. We introduce a robot-assisted technique to enhance the accuracy and reduce the tedium of the procedure. MATERIALS AND METHODS:Laser burn locations are overlaid on preoperative retinal images using common patterns such a...

journal_title：Lasers in surgery and medicine

authors： Becker BC,MacLachlan RA,Lobes LA Jr,Riviere CN

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Intense pulsed light (IPL) is regarded as the gold standard of nonablative photo-rejuvenation. Yet there is still a need to observe its efficacy and safety on dark skin using a split-face module. STUDY DESIGN/MATERIALS AND METHODS:Twenty-four Chinese women with photoaging were enrolled in thi...

journal_title：Lasers in surgery and medicine

authors： Li YH,Wu Y,Chen JZ,Zhu X,Xu YY,Chen J,Dong GH,Gao XH,Chen HD

更新日期：2010-02-01 00:00:00